Steve Tomasula's work exists at the cutting edges of scientific knowledge and literary techniques. As such, it demands consideration from multiple perspectives and from critics who can guide the reader through the formal innovations and multimedia involutions while providing critical scientific, aesthetic, historical, and technical contexts. This book, the first of its kind, provides this framework, showing readers the richness and relevance of the worlds Tomasula constructs. Steve Tomasula's work is redefining the form of the novel, reinventing the practice of reading, and wrestling with the most urgent questions raised by massive transformations of media and biotechnologies. His work not only charts these changes, it formulates the problems that we have making meaning in our radically changing technological contexts. Vast in scope, inventive in form, and intimate in voice, his novels, short stories, and essays are read and taught by a surprisingly diverse array of scholars in fields ranging from contemporary experimental writing and literary criticism to the history of science, biotechnology and bioart, book studies, and digital humanities.